Tracheal Stenosis Related to Ulcerative Colitis

Background: Ulcerative colitis (UC) is a chronic inflammatory disease of the intestines. UC-related respiratory disease is fairly rare. Early diagnosis is important and can prevent significant potential effects, but can be challenging, due to mild symptoms and inconclusive radiology findings. This r...

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Bibliographic Details
Published inErciyes Medical Journal Vol. 44; no. 2; p. 239
Main Authors Dirol, Hulya, Amiraslanov, Turbat, Ozdemir, Tulay, Celik, Mennan Yigitcan, Ozbilim, Gulay
Format Journal Article
LanguageEnglish
Published Istanbul KARE Publishing 01.03.2022
Kare Publishing
Subjects
Case studies
Complications and side effects
Stenosis
Trachea
Ulcerative colitis
Turkey
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Summary:Background: Ulcerative colitis (UC) is a chronic inflammatory disease of the intestines. UC-related respiratory disease is fairly rare. Early diagnosis is important and can prevent significant potential effects, but can be challenging, due to mild symptoms and inconclusive radiology findings. This report describes some elements that can assist with early diagnosis. Case Report: A 41-year-old female with diagnosed UC and Takayasu arteritis presented with a dry cough ongoing for 3 weeks. The patient had experienced no recent symptoms related to UC and had discontinued use of medication. A pulmonary function test (PFT) indicated an obstruction during inhalation and exhalation in the flow-volume loop. Irregular diffuse tracheal wall thickening was observed on chest computed tomography images. Bronchoscopy revealed that the trachea/bronchus had a rough, hyperemic appearance. Lymphoplasmacytic inflammation observed in the bronchus biopsy sample was compatible with UC-related respiratory disease. No symptoms or obstruction were seen in the PFT after 2 months of treatment with azathioprine and methylprednisolone. Conclusion: Early bronchoscopy in patients with unclear radiological findings is important for an early diagnosis and the prevention of potentially irreversible complications in UC-related respiratory disease. Keywords: Bronchi, stenosis, trachea, ulcerative colitis, vasculitis
ISSN:2149-2247
2980-2156
DOI:10.14744/etd.2021.85226