Oral polymeric N-acetyl-D-glucosamine and osteoarthritis

Many patients with arthritis are using alternative modes of therapy, including nutritional supplements, to treat their arthritis. Most patients never tell their doctors that they are taking alternative medications, and few doctors even ask about such activities. Over-the-counter supplements are expe...

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Bibliographic Details
Published inThe Journal of the American Osteopathic Association Vol. 101; no. 6; p. 339
Main Authors Rubin, B R, Talent, J M, Kongtawelert, P, Pertusi, R M, Forman, M D, Gracy, R W
Format Journal Article
LanguageEnglish
Published United States 01.06.2001
Subjects
Acetylglucosamine - administration & dosage
Administration, Oral
Adult
Cross-Over Studies
Dose-Response Relationship, Drug
Double-Blind Method
Female
Glucosamine - administration & dosage
Humans
Male
Middle Aged
Osteoarthritis - diagnosis
Osteoarthritis - drug therapy
Pain Measurement
Pilot Projects
Range of Motion, Articular - drug effects
Sensitivity and Specificity
Treatment Outcome
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Summary:Many patients with arthritis are using alternative modes of therapy, including nutritional supplements, to treat their arthritis. Most patients never tell their doctors that they are taking alternative medications, and few doctors even ask about such activities. Over-the-counter supplements are expensive and consume large amounts of patients' healthcare dollars. Glucosamine has been widely touted as being an effective arthritis treatment. The authors designed and undertook a study to test the efficacy of a polymer of N-acetyl-D-glucosamine (NAG), or POLY-Nag, in a double-blind, placebo-controlled study in patients with osteoarthritis. Results indicate that POLY-Nag may be useful in treating patients with osteoarthritis.
ISSN:0098-6151
1945-1997