Analysis of the Peptidoglycan Hydrolase Complement of Lactobacillus casei and Characterization of the Major [gamma]-D-Glutamyl-L-Lysyl-Endopeptidase

Peptidoglycan (PG) is the major component of Gram positive bacteria cell wall and is essential for bacterial integrity and shape. Bacteria synthesize PG hydrolases (PGHs) which are able to cleave bonds in their own PG and play major roles in PG remodelling required for bacterial growth and division....

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Published inPloS one Vol. 7; no. 2; p. e32301
Main Authors Regulski, Krzysztof, Courtin, Pascal, Meyrand, Mickael, Claes, Ingmar J. J, Lebeer, Sarah, Vanderleyden, Jos, Hols, Pascal, Guillot, Alain, Chapot-Chartier, Marie-Pierre
Format Journal Article
LanguageEnglish
Published Public Library of Science 27.02.2012
Subjects
Analysis
Bacteria
Genetic aspects
Genomes
Genomics
Hydrolases
Oligomers
Probiotics
Transcription (Genetics)
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Summary:Peptidoglycan (PG) is the major component of Gram positive bacteria cell wall and is essential for bacterial integrity and shape. Bacteria synthesize PG hydrolases (PGHs) which are able to cleave bonds in their own PG and play major roles in PG remodelling required for bacterial growth and division. Our aim was to identify the main PGHs in Lactobacillus casei BL23, a lactic acid bacterium with probiotic properties.
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0032301