Electronic control of H.sup.+ current in a bioprotonic device with carbon nanotube porins

Hybrid biotic abiotic devices can be used to interface electronics with biological systems for novel therapies or to increase device functionality beyond silicon. Many strategies exist to merge the electronic and biological worlds, one dominated by electrons and holes as charge carriers, the other b...

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Bibliographic Details
Published inPloS one Vol. 14; no. 2; p. e0212197
Main Authors Hemmatian, Zahra, Tunuguntla, Ramya H, Noy, Aleksandr, Rolandi, Marco
Format Journal Article
LanguageEnglish
Published Public Library of Science 22.02.2019
Subjects
Analysis
Cell membranes
Electrons
Ion channels
Machinery
Membrane lipids
Nanotubes
Novels
Porins
Silicon
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Summary:Hybrid biotic abiotic devices can be used to interface electronics with biological systems for novel therapies or to increase device functionality beyond silicon. Many strategies exist to merge the electronic and biological worlds, one dominated by electrons and holes as charge carriers, the other by ions. In the biological world, lipid bilayers and ion channels are essential to compartmentalize the cell machinery and regulate ionic fluxes across the cell membrane. Here, we demonstrate a bioelectronic device in which a lipid bilayer supported on H.sup.+ -conducting Pd/PdH.sub.x contacts contains carbon nanotubes porin (CNTP) channels. This bioelectronic device uses CNTPs to control of H.sup.+ flow across the lipid bilayer with a voltage applied to the Pd/PdH.sub.x contacts. Potential applications of these devices include local pH sensing and control.
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0212197