Parathyroid carcinoma: difficult management options

Parathyroid carcinoma is a rare cause of primary hyperparathyroidism and these tumours are usually hyperfunctional as opposed to other malignant endocrine tumors. Surgery is the only effective treatment while nonsurgical modalities yield poor results. We report a patient, who presented with palpable...

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Bibliographic Details
Published inIndian journal of cancer Vol. 39; no. 3; p. 119
Main Authors Bhansali, A, Kataria, R N, Dutta, P, Saha, M M, Singh, P, Dash, R J
Format Journal Article
LanguageEnglish
Published India Medknow Publications and Media Pvt. Ltd 01.07.2002
Subjects
Adult
Alcohols - therapeutic use
Alendronate - therapeutic use
Antineoplastic Agents, Alkylating - therapeutic use
Calcitonin - therapeutic use
Care and treatment
Combined Modality Therapy
Dacarbazine - therapeutic use
Diagnosis
Endocrine gland cancer
Humans
Hypercalcemia
Hypercalcemia - drug therapy
Hypercalcemia - etiology
Male
Parathyroid diseases
Parathyroid Neoplasms - complications
Parathyroid Neoplasms - drug therapy
Parathyroid Neoplasms - surgery
India
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Summary:Parathyroid carcinoma is a rare cause of primary hyperparathyroidism and these tumours are usually hyperfunctional as opposed to other malignant endocrine tumors. Surgery is the only effective treatment while nonsurgical modalities yield poor results. We report a patient, who presented with palpable mass in the neck and severe hypercalcemia. He underwent debulking surgery and received allendronate, calcitonin, dacarbazine followed by in- situ alcohol instillation with some success.
ISSN:0019-509X