Buccal mucosa as a route for systemic drug delivery: a review

Within the oral mucosal cavity, the buccal region offers an attractive route of administration for systemic drug delivery. The mucosa has a rich blood supply and it is relatively permeable. It is the objective of this article to review buccal drug delivery by discussing the structure and environment...

Full description

Saved in:
Bibliographic Details
Published inJournal of pharmacy & pharmaceutical sciences Vol. 1; no. 1; pp. 15 - 30
Main Author Shojaei, A H
Format Journal Article
LanguageEnglish
Published Canada 01.01.1998
Subjects
Absorption
Administration, Oral
Animals
Biological Transport
Drug Delivery Systems
Humans
Mouth Mucosa - anatomy & histology
Mouth Mucosa - metabolism
Permeability
Pharmaceutical Preparations - administration & dosage
Pharmaceutical Preparations - metabolism
Polymers
Online AccessGet full text

Cover

More Information
Summary:Within the oral mucosal cavity, the buccal region offers an attractive route of administration for systemic drug delivery. The mucosa has a rich blood supply and it is relatively permeable. It is the objective of this article to review buccal drug delivery by discussing the structure and environment of the oral mucosa and the experimental methods used in assessing buccal drug permeation/absorption. Buccal dosage forms will also be reviewed with an emphasis on bioadhesive polymeric based delivery systems
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
ISSN:1482-1826