Social Cognition Mediates the Impact of Processing Speed and Sustained Attention on Global Functioning in Schizophrenia/La Cognicion Social Media el Impacto de la Velocidad de Procesamiento y la Atencion Sostenida Sobre el Funcionamiento Global en Esquizofrenia

Background: Deficits in information processing, sustained attention and social cognition have important implications for the daily functioning of people with schizophrenia. The present study analyzed the relationship between processing speed, sustained attention, social cognition, and functioning in...

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Published inPsicothema Vol. 35; no. 1; p. 87
Main Authors Ruiz-Toca, Alicia, Fernandez-Aragon, Cristina, Madrigal, Ana, Halverson, Tate, Rodriguez-Jimenez, Roberto, Lahera, Guillermo
Format Journal Article
LanguageEnglish
Published Colegio Oficial De Psicologos Del Principado De Asturias 01.01.2023
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Summary:Background: Deficits in information processing, sustained attention and social cognition have important implications for the daily functioning of people with schizophrenia. The present study analyzed the relationship between processing speed, sustained attention, social cognition, and functioning in clinically stable people with schizophrenia. Method: Ninety people with schizophrenia and 100 healthy controls completed a battery of measures to assess clinical symptoms, processing speed, sustained attention, social cognition, and functioning. GLMMs and SEM were used to assess the relationships between these variables. Results: People with schizophrenia had impaired performance in all cognitive outcomes compared to healthy controls. Processing speed and sustained attention, together in a latent variable, had a strong effect on functioning (Beta = 0.32; p < .05). However, social cognition had also a strong effect on functioning (Beta = 0.29; p <.001) in the mediation model, which exhibited better indices of fit than the model including neurocognition alone (e.g. RMSEAbasic = 0.131 and RMSEAmediator = 0.054). Conclusions: The mediating effect of social cognition on the relationship between processing speed, sustained attention, and functioning in people with schizophrenia suggests the importance of including both domains of neurocognition along with social cognition as treatment targets in rehabilitation interventions to optimize improvements in functioning in schizophrenia. Keywords: Processing speed Sustained attention Social cognition Schizophrenia Psychosis Antecedentes: Los deficits en el procesamiento de la informacion, la atencion sostenida y la cognicion social tienen implicaciones importantes para el funcionamiento diario de las personas con esquizofrenia. El presente estudio analizo la relacion entre velocidad de procesamiento, atencion sostenida, cognicion social y funcionamiento en personas clinicamente estables con esquizofrenia. Metodo: Noventa personas con esquizofrenia y 100 controles sanos completaron una bateria de pruebas para evaluar sintomas clinicos, velocidad de procesamiento, atencion sostenida, cognicion social y funcionamiento. Se utilizaron GLMM y SEM para evaluar las relaciones entre variables. Resultados: Las personas con esquizofrenia tuvieron un peor rendimiento en todos los resultados cognitivos. La velocidad de procesamiento y la atencion sostenida, juntas en una variable latente, tuvieron un fuerte effecto sobre el funcionamiento (Beta = 0,32; p < 0,05). La cognicion social tambien tuvo un fuerte effecto sobre el funcionamiento (Beta = 0,29; p < 0,001) en el modelo de mediacion, que mostro mejores indices de ajuste que el modelo que incluia solo neurocognicion (e.g. RMSEAbasic = 0.131 y RMSEAmediator = 0.054). Conclusiones: El effecto mediador de la cognicion social sobre la relacion entre la velocidad de procesamiento, la atencion sostenida y el funcionamiento sugiere la importancia de incluir ambos dominios junto con la cognicion social como objetivos de tratamiento en las intervenciones de rehabilitacion. Palabras clave: Velocidad de procesamiento Atencion sostenida Cognicion social Esquizofrenia Psicosis
ISSN:0214-9915
1886-144X
DOI:10.7334/psicothema2022.8