IPoria cocos/I Lanostane Triterpenoids Extract Promotes Collagen and Hyaluronic Acid Production in D-Galactose-Induced Aging Rats

The global aging population is expanding at an increasingly rapid pace, with approximately one-fourth of the world’s population expected to be composed of elderly individuals by 2050. Aging skin is one of the major characteristics expressed in the elderly. The study comprehensively utilizes both cel...

Full description

Saved in:
Bibliographic Details
Published inLife (Basel, Switzerland) Vol. 13; no. 11
Main Authors Chao, Chien-Liang, Kuo, Han-Peng, Huang, Hsin-Wen, Cheng, Maw-Yeun, Chao, Hsin-Fan, Lu, Shih-Min, Lin, Hang-Ching, Wang, Chao-Jih, Chang, Tsu-Chung, Wu, Chi-Rei
Format Journal Article
LanguageEnglish
Published MDPI AG 01.10.2023
Subjects
Aging
Basidiomycota
Chemical properties
Collagen
Health aspects
Hyaluronic acid
Medicine, Chinese
Pharmacology, Experimental
Skin
Terpenoids
Taiwan
Online AccessGet full text

Cover

More Information
Summary:The global aging population is expanding at an increasingly rapid pace, with approximately one-fourth of the world’s population expected to be composed of elderly individuals by 2050. Aging skin is one of the major characteristics expressed in the elderly. The study comprehensively utilizes both cell and animal experiments to confirm the skin anti-aging effects of Poria cocos (P. cocos), which is one of the most important traditional Chinese medicines classified as tonic Chinese medicine, commonly used to treat physical weakness and aging-associated diseases. We demonstrate in this study that P. cocos lanostane triterpenoids extract (Lipucan[sup.®] ) ameliorates aging skin and promotes collagen accumulation and hyaluronic acid production in galactose-induced aging rats. Purified lanostane triterpenoids were initially identified as active components in P. cocos, which significantly increased collagen and hyaluronic acid levels in cultured human skin cells.
ISSN:2075-1729
2075-1729
DOI:10.3390/life13112130