OXIDANT AND ANTIOXIDANT STATUS IN CRF

Oxidative stress plays a significant role in pathogenesis of chronic renal failure (CRF). Redox imbalance caused by increased ROS production and/or reduced antioxidant reserve, leading to pathological consequences including damage to proteins, lipids and DNA. The present paper focuses on the extent...

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Published inIndian journal of clinical biochemistry Vol. 27; no. S1; p. S21
Main Authors Priya, Ratna, Keshri, J.R, Kumar, Uday, Sharan, Anand, Kumari, Rekha, Kishore, Chandan, Priya, Jyoti
Format Journal Article
LanguageEnglish
Published Springer 24.05.2022
Subjects
Antioxidants
Chronic kidney failure
Lipids
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Summary:Oxidative stress plays a significant role in pathogenesis of chronic renal failure (CRF). Redox imbalance caused by increased ROS production and/or reduced antioxidant reserve, leading to pathological consequences including damage to proteins, lipids and DNA. The present paper focuses on the extent of free radical damage on lipid (measured as malondialdehyde, MDA) and effect on antioxidant defense mechanism (measured as vitamin C) in the serum of CRF patients predialytically .40 cases and 40 controls between age group of 25-60 were taken.
ISSN:0970-1915