Robustness in crossover regulation during meiosis: meiotic recombination produces physical linkages between homologous chromosomes that enable their segregation to opposite poles during meiosis I. In the absence of recombination, chromosomes mis-segregate, resulting in aneuploidy associated with severe birth defects. A recent study provides exciting insights into how recombination is fine-tuned to enforce a robust meiotic program

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Bibliographic Details
Published inNature cell biology Vol. 14; no. 4; pp. 335 - 337
Main Author Kotwaliwale, Chitra V
Format Journal Article
LanguageEnglish
Published Nature Publishing Group 01.04.2012
Subjects
Chromosomes
Genetic recombination
Meiosis
Physiological aspects
United States
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ISSN:1465-7392
1476-4679