Precision Cancer Care: Preserving Normal Tissue With Proton Therapy

Proton therapy can also be delivered on the millimeter scale using pencil beam scanning (PBS), which ensures precise treatment in the desired areas. Because of the sharp dose falloff, extra care must be taken during treatment to account for changes in the tumor, such as tissue swelling, tumor shrink...

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Bibliographic Details
Published inOncology live
Main Author Skalina, Karin A
Format Journal Article
LanguageEnglish
Published Cranbury Intellisphere, LLC 20.05.2024
MultiMedia Healthcare Inc
Subjects
Cancer
Cancer patients
Cancer therapies
Care and treatment
Chemotherapy
Clinical trials
Heart
Human papillomavirus
Metastasis
Oncology
Patients
Protons
Radiation
Radiation therapy
Radiotherapy
Spinal cord
Tumors
New York
United States > US
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Summary:Proton therapy can also be delivered on the millimeter scale using pencil beam scanning (PBS), which ensures precise treatment in the desired areas. Because of the sharp dose falloff, extra care must be taken during treatment to account for changes in the tumor, such as tissue swelling, tumor shrinkage, and/or a shift in its location due to weight loss during treatment, in the path of beam to ensure the Bragg peak remains in the target region. [...]patients undergoing proton therapy may require additional scans and potential changes to their treatment plan over the course of their therapy to account for any anatomical changes. The Department of Radiation Oncology at Montefiore Einstein Comprehensive Cancer Center (MECCC) routinely refers these cases to the NYPC under the care and supervision of their MECCC radiation oncologist. Because of his young age and the proximity of the tumor to his heart, he was referred to NYPC where we generated a comparison plan using conventional radiation techniques, which clearly demonstrated that protons would reduce the radiation dose to the heart by approximately 50% and to the spinal cord by one-third. The benefit of proton therapy in this model was especially apparent in younger patients with minimal smoking history (no more than 10 years) whose oropharyngeal tumors were driven by human papillomavirus (HPV).6 A separate computer model was devised to determine the individual quality-of-life benefit and cost-effectiveness of proton therapy for patients with oropharyngeal cancer.
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ISSN:2374-5347
2767-4924