Phytochemical Constituents from the Aerial Parts of Paris verticillata

Column chromatographic separation of the MeOH extract from the aerial parts of Paris verticillata led to the isolation of three phenolics, two terpene glucosides and two pyrrolidine alkaloids. Their structures were characterized to be methyl caffeate (1), 5-hydroxy pyrrolidin-2-one (2), vanillic aci...

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Published inKorean Journal of Pharmacognosy Vol. 39; no. 2
Main Authors Lee, K.H. (Sungkyunkwan University, Suwon, Republic of Korea), Kim, K.H. (Sungkyunkwan University, Suwon, Republic of Korea), Lee, I.K. (Sungkyunkwan University, Suwon, Republic of Korea), Choi, S.U. (Korea Research Institute of Chemical Technology, Daejeon, Republic of Korea), Lee, K.R. (Sungkyunkwan University, Suwon, Republic of Korea), E-mail: krlee@skku.ac.kr
Format Journal Article
LanguageKorean
Published 01.06.2008
Subjects
COMPOSE PHENOLIQUE
COMPUESTOS FENOLICOS
LILIACEAE
Paris verticillata
PHENOLIC COMPOUNDS
Pyrrolidine alkaloid
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Summary:Column chromatographic separation of the MeOH extract from the aerial parts of Paris verticillata led to the isolation of three phenolics, two terpene glucosides and two pyrrolidine alkaloids. Their structures were characterized to be methyl caffeate (1), 5-hydroxy pyrrolidin-2-one (2), vanillic acid (3), benzyl alcohol glucopyranoside (4), (6S, 9R)-roseoside (5), staphylionoside H (6) and 5-methoxy pyrrolidin-2-one (7) by spectroscopic means. The isolated compounds (1-7) were for the first time reported from this source. The isolated compounds were tested for their cytotoxicity against four human tumor cell lines by SRB method in vitro.
Bibliography:2009002598
F60
ISSN:0253-3073