Single oral high-dose vitamin D3 prophylaxis in the elderly

During the winter months, poor vitamin D status among the elderly is common. In this study, a single high dose of oral vitamin D was tested in two homes for the elderly. The two types of vitamin D given were: vitamin D3 and 25-hydroxyvitamin D3 (25-OHD3). Four to five month follow ups showed that th...

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Published inJournal of the American Geriatrics Society (JAGS) Vol. 34; no. 7; p. 515
Main Authors Weisman, Y, Schen, R J, Eisenberg, Z, Amarilio, N, Graff, E, Edelstein-Singer, M, Goldray, D, Harell, A
Format Journal Article
LanguageEnglish
Published United States 01.07.1986
Subjects
Aged
Calcifediol - administration & dosage
Calcifediol - blood
Cholecalciferol - administration & dosage
Clinical Trials as Topic
control de enfermedades
controle de maladies
disease control
Female
Homes for the Aged
Humans
Intestinal Absorption - drug effects
Male
Seasons
Time Factors
vitamin d
Vitamin D Deficiency - blood
Vitamin D Deficiency - prevention & control
vitamina d
vitaminas
vitamine
vitamine d
vitamins
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Summary:During the winter months, poor vitamin D status among the elderly is common. In this study, a single high dose of oral vitamin D was tested in two homes for the elderly. The two types of vitamin D given were: vitamin D3 and 25-hydroxyvitamin D3 (25-OHD3). Four to five month follow ups showed that those subjects who had received the single oral dose of 25-OHD3 returned to their previous low serum levels, while serum vitamin D levels were still high in subjects receiving the oral vitamin D3. The research suggests that vitamin D3 prophylaxis is a safe and effective method of improving vitamin D status in the elderly population.(lsp).
Bibliography:S30
S
ISSN:0002-8614
1532-5415
DOI:10.1111/j.1532-5415.1986.tb04243.x