Concepts for the clinical use of stem cells in equine medicine

Stem cells from various tissues hold great promise for their therapeutic use in horses, but so far efficacy or proof-of-principle has not been established. The basic characteristics and properties of various equine stem cells remain largely unknown, despite their increasingly widespread experimental...

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Published inCanadian veterinary journal Vol. 49; no. 10; pp. 1009 - 1017
Main Authors Koch, Thomas G, Berg, Lise C, Betts, Dean H
Format Journal Article
LanguageEnglish
Published Canada Canadian Veterinary Medical Association 01.10.2008
Subjects
Animals
cell biology
Cell Differentiation - physiology
Horse Diseases - therapy
Horses
literature reviews
Scientific
Stem Cell Transplantation - veterinary
stem cells
Stem Cells - physiology
Tissue Engineering - veterinary
veterinary medicine
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Summary:Stem cells from various tissues hold great promise for their therapeutic use in horses, but so far efficacy or proof-of-principle has not been established. The basic characteristics and properties of various equine stem cells remain largely unknown, despite their increasingly widespread experimental and empirical commercial use. A better understanding of equine stem cell biology and concepts is needed in order to develop and evaluate rational clinical applications in the horse. Controlled, well-designed studies of the basic biologic characteristics and properties of these cells are needed to move this new equine research field forward. Stem cell research in the horse has exciting equine specific and comparative perspectives that will most likely benefit the health of horses and, potentially, humans.
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Dr. Koch is currently enrolled in a PhD program at the University of Guelph, Canada, funded by an international grant from the Danish Research Council. Additional operating funds are provided by the Equine Guelph Research Fund and its partners; E.P. Taylor Equine Research Fund, The Horsemen’s Benevolent and Protective Association of Ontario, Ontario Equestrian Federation, Ontario Harness Horse Association, Ontario Ministry of Agriculture and Food, Ontario Racing Commission, Ontario Veterinary College, University of Guelph.
ISSN:0008-5286