Antimicrobial resistance of fecal Salmonella spp. isolated from all phases of pig production in 20 herds in Alberta and Saskatchewan

• Published in: Canadian journal of veterinary research Vol. 72; no. 2; pp. 151 - 159
• Main Authors: Rosengren, L.B, Waldner, C.L, Reid-Smith, R.J, Checkley, S.L, McFall, M.E, Rajic, A
• Format: Journal Article
• Language: English
• Published: Canada Canadian Veterinary Medical Association 01.01.2008
• Subjects: Age Factors; Alberta; Animals; Anti-Bacterial Agents - pharmacology; antibiotic resistance; antimicrobial agents; Colony Count, Microbial - veterinary; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; feces; Feces - microbiology; Female; Male; Microbial Sensitivity Tests; Risk Factors; Salmonella; Salmonella - drug effects; Salmonella - isolation & purification; Salmonella Infections, Animal - drug therapy; Salmonella Infections, Animal - microbiology; Saskatchewan; Swine; Swine Diseases - drug therapy; Swine Diseases - microbiology; Alberta; Saskatchewan
• ISSN: 0830-9000

Salmonella spp. (n = 468), isolated from the feces of sows, nursery, and grow-finish pigs in 20 farrow-to-finish herds in Alberta and Saskatchewan, were tested for susceptibility to 16 antimicrobials. No resistance was identified to amikacin, amoxicillin-clavulanic acid, ceftiofur, ceftriaxone, ciprofloxacin or nalidixic acid, and less than 1% of the isolates were resistant to cefoxitin and gentamicin. Isolates were most commonly resistant to tetracycline (35%) and sulfamethoxazole (27%). Overall, 59% of the Salmonella were susceptible to all 16 drugs (pansusceptible). Isolates from sows were more likely to be pansusceptible than isolates from nursery or grow-finish pigs. Resistance to 2 or more drugs occurred in 29% of the isolates and was significantly more likely to occur in Salmonella from nursery pigs than from sows. The odds of resistance to 4 of the drugs, streptomycin, ampicillin, kanamycin and cephalothin, were significantly higher in isolates from nursery pigs than grow-finish pigs, while the odds of resistance to 2 drugs, tetracycline and streptomycin, were higher in Salmonella from nursery pigs than from sows. More age-specific risk factor studies are needed to investigate these differences between production phases.