Evaluation of Melia volkensii extract fractions as mosquito larvicides

A standardized fraction of Melia volkensii fruit kernel extract was tested against Anopheles arabiensis mosquito larvae. The LC50 in 48 hr was 5.4 micrograms/ml. At low concentrations this fraction had growth inhibiting activity producing prolonged larval instars, and lethal effects during ecdysis....

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Bibliographic Details
Published inJournal of the American Mosquito Control Association Vol. 4; no. 4; p. 442
Main Authors Mwangi, R.W, Mukiama, T.K
Format Journal Article
LanguageEnglish
Published United States 01.12.1988
Subjects
Animals
ANOPHELES
ANOPHELES ARABIENSIS
Chromatography, Thin Layer
CONTROL DE INSECTOS
EXTRACTOS VEGETALES
EXTRAIT D'ORIGINE VEGETALE
INSECT CONTROL
INSECTICIDAS
INSECTICIDE
INSECTICIDES
Juvenile Hormones
KENIA
KENYA
Larva
LARVAE
LARVAS
LARVE
LUTTE ANTI-INSECTE
MELIACEAE
Mosquito Control - methods
PLANT EXTRACTS
Plant Extracts - pharmacology
Temperature
VECTEUR
VECTORES
VECTORS
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Summary:A standardized fraction of Melia volkensii fruit kernel extract was tested against Anopheles arabiensis mosquito larvae. The LC50 in 48 hr was 5.4 micrograms/ml. At low concentrations this fraction had growth inhibiting activity producing prolonged larval instars, and lethal effects during ecdysis. Further fractionation of the standardised fraction yielded seven bands on preparative Thin Layer Chromatography. The two most lipophilic bands had acute toxic effects on the larvae, the next two bands had growth inhibiting effects, while the three trailing bands had no effect at all. The acute toxicity and growth inhibiting effects were destroyed by heat during the drying of the fruits.
Bibliography:L72
8900921
ISSN:8756-971X
1943-6270