Molecular Basis of Arabinobio-hydrolase Activity in Phytopathogenic Fungi: CRYSTAL STRUCTURE AND CATALYTIC MECHANISM OF FUSARIUM GRAMINEARUM GH93 EXO-α-L-ARABINANASE

• Published in: The Journal of biological chemistry Vol. 284; no. 18; pp. 12285 - 12296
• Main Authors: Carapito, Raphaël, Imberty, Anne, Jeltsch, Jean-Marc, Byrns, Simon C, Tam, Pui-Hang, Lowary, Todd L, Varrot, Annabelle, Phalip, Vincent
• Format: Journal Article
• Language: English
• Published: United States American Society for Biochemistry and Molecular Biology 01.05.2009
• Subjects: Crystallography, X-Ray; Fungal Proteins - chemistry; Fusarium - enzymology; Glycoside Hydrolases - chemistry; Life Sciences; Models, Chemical; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Polysaccharides; Protein Structure, Secondary - physiology; Protein Structure, Tertiary - physiology; Vegetal Biology

The phytopathogenic fungus Fusarium graminearum secretes a very diverse pool of glycoside hydrolases (GHs) aimed at degrading plant cell walls. α-L-Arabinanases are essential GHs participating in the complete hydrolysis of hemicellulose, a natural resource for various industrial processes, such as b...