Hemoglobin enhancement of experimental infection of mice with Pasteurella haemolytica

A 2% hemoglobin preparation injected into mice along with Pasteurella haemolytica culture was found to be as good an enhancer of virulence as a 7% swine gastric mucin preparation. The hemoglobin preparation was easier to prepare and was less toxic than mucin for mice when injected intraperitoneally.

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Bibliographic Details
Published inAmerican journal of veterinary research Vol. 44; no. 8; p. 1545
Main Authors Chengappa, M.M, Carter, G.R, Chang, T.S
Format Journal Article
LanguageEnglish
Published United States 01.08.1983
Subjects
Animals
Cattle - microbiology
Chickens - microbiology
Disease Models, Animal
Gastric Mucins - pharmacology
Hemoglobins
Iron - pharmacology
Lung - microbiology
Male
Mice
Mice, Inbred Strains - microbiology
Pasteurella - pathogenicity
Pasteurella Infections - microbiology
Pasteurella Infections - veterinary
Rodent Diseases - microbiology
Sheep - microbiology
Swine
Virulence - drug effects
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Summary:A 2% hemoglobin preparation injected into mice along with Pasteurella haemolytica culture was found to be as good an enhancer of virulence as a 7% swine gastric mucin preparation. The hemoglobin preparation was easier to prepare and was less toxic than mucin for mice when injected intraperitoneally.
Bibliography:8281648
L73
ISSN:0002-9645
1943-5681