Hepatitis in a dog given sulfadiazine-trimethoprim and cyclophosphamide

Vomiting, diarrhea, icterus and elevated serum alkaline phosphatase, SGPT and serum bilirubin levels occurred in a 12-year-old Basenji on sulfadiazine-trimethoprim and cyclophosphamide therapy. After use of the antibacterial drug was discontinued, the dog returned to normal with no further evidence...

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Bibliographic Details
Published inModern Veterinary Practice Vol. 65; no. 2; p. 115
Main Authors Anderson, W I, Campbell, K L, Wilson, R C, Goetsch, D D
Format Journal Article
LanguageEnglish
Published United States 01.02.1984
Subjects
Animals
Anti-Infective Agents, Urinary - adverse effects
Chemical and Drug Induced Liver Injury - veterinary
Cyclophosphamide - therapeutic use
Dog Diseases - chemically induced
Dog Diseases - drug therapy
Dogs
Drug Combinations - adverse effects
Drug Therapy, Combination
Female
Male
Sulfadiazine - adverse effects
Trimethoprim - adverse effects
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Summary:Vomiting, diarrhea, icterus and elevated serum alkaline phosphatase, SGPT and serum bilirubin levels occurred in a 12-year-old Basenji on sulfadiazine-trimethoprim and cyclophosphamide therapy. After use of the antibacterial drug was discontinued, the dog returned to normal with no further evidence of hepatocellular damage.
Bibliography:L
L73
ISSN:0362-8140