A technique for liver biopsy performed in Pekin ducks using anesthesia with Telazol

Infection of Pekin ducks with duck hepatitis B virus is a useful model for studying the hepadenoviruses, of which human hepatitis B virus is the prototype. The utility of this model has been limited, however, by the difficulties associated with anesthetizing and obtaining liver biopsies from ducks....

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Published inLaboratory animal science (Chicago) Vol. 41; no. 5; p. 474
Main Authors Carp, N.Z. (Fox Chase Cancer Center, Philadelphia, PA), Saputelli, J, Halbherr, T.C, Mason, W.S, Jilbert, A.R
Format Journal Article
LanguageEnglish
Published United States 01.10.1991
Subjects
ANESTESIA
ANESTESICOS
ANESTHESIE
ANESTHESIQUE
Anesthetics, Dissociative
Animals
BIOPSIA
BIOPSIE
Biopsy - methods
CANARD
Drug Combinations
Ducks - surgery
ENTEROVIRUS
FOIE
Hepatitis B Virus, Duck
Hepatitis, Viral, Animal - etiology
Hepatitis, Viral, Animal - pathology
HIGADO
Liver - pathology
PATO
SECURITE
SEGURIDAD
Tiletamine
Zolazepam
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Summary:Infection of Pekin ducks with duck hepatitis B virus is a useful model for studying the hepadenoviruses, of which human hepatitis B virus is the prototype. The utility of this model has been limited, however, by the difficulties associated with anesthetizing and obtaining liver biopsies from ducks. We developed a technique using Telazol, (13 mg/kg) to anesthetize ducks before surgical biopsy of the liver in ducks infected with duck hepatitis B virus. Eight Pekin ducks infected with duck hepatitis B virus underwent serial biopsies at 4- to 5-week intervals. There was one perioperative death in 34 surgical procedures with no evidence on intra-abdominal sepsis or wound complications. Telazol can be used safely and humanely to anesthetize ducks without the need for general endotracheal anesthesia
Bibliography:9300913
L70
ISSN:0023-6764