Renal functional relationships in dogs with glomerulopathies

Glomerular filtration rate, effective renal plasma flow, and filtration fraction were determined by measuring plasma disappearance of [14C] inulin and [3H]tetraethylammonium bromide after a single IV bolus injection was given to 8 dogs with membranous nephropathy, renal glomerulosclerosis, or renal...

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Bibliographic Details
Published inAmerican journal of veterinary research Vol. 48; no. 4; p. 610
Main Authors Allen, T.A, Fettman, M.J, Jaenke, R.S, Wilke, W.L
Format Journal Article
LanguageEnglish
Published United States 01.04.1987
Subjects
Animals
BASES
Blood Flow Velocity
CHIEN
CREATININA
CREATININE
Dog Diseases - physiopathology
DOGS
ENFERMEDADES RENALES
Female
FILTRACION
FILTRATION
FONCTION PHYSIOLOGIQUE
FUNCION FISIOLOGICA
Glomerular Filtration Rate
HIDROXIDOS
HYDROXIDES
HYDROXYDE
INULIN
INULINA
INULINE
KIDNEY DISEASES
Kidney Diseases - physiopathology
Kidney Diseases - veterinary
Kidney Glomerulus - physiopathology
KIDNEYS
Male
NEPHROPATHIE
PERRO
PHYSIOLOGICAL FUNCTIONS
REIN
Renal Circulation
RINONES
Tetraethylammonium
tetraethylammonium bromide
Tetraethylammonium Compounds
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Summary:Glomerular filtration rate, effective renal plasma flow, and filtration fraction were determined by measuring plasma disappearance of [14C] inulin and [3H]tetraethylammonium bromide after a single IV bolus injection was given to 8 dogs with membranous nephropathy, renal glomerulosclerosis, or renal amyloidosis. Glomerular filtration rate was decreased in the 8 dogs. Effective renal plasma flow was within reference values in 1 dog, increased in 1 dog, and decreased in 6 dogs. Filtration fraction was within reference values in 2 dogs and decreased in 6 dogs. The glomerular filtration rate also was estimated by the endogenous creatinine clearance technique and was decreased in the 8 dogs with glomerulopathies.
Bibliography:L74
8728473
ISSN:0002-9645
1943-5681