Energy balances of eight volunteers fed on diets supplemented with either lactitol or saccharose

• Published in: British journal of nutrition Vol. 56; no. 3; pp. 545 - 554
• Main Authors: Es, A.J.H. van, Groot, L. de, Vogt, J.E
• Format: Journal Article
• Language: English
• Published: Wallingford Cambridge University Press 1986
• Subjects: Adult; Biological and medical sciences; Body Temperature Regulation - drug effects; diet; energy balance; Energy Metabolism - drug effects; Feces - analysis; Feeding. Feeding behavior; Food, Fortified; Fundamental and applied biological sciences. Psychology; Fysiologie van Mens en Dier; Gases - biosynthesis; Human and Animal Physiology; Humans; lactitol; Leerstoelgroep Fysiologie van mens en dier; Nitrogen - analysis; Nitrogen - urine; nitrogen metabolism; Respiration - drug effects; sucrose; Sucrose - pharmacology; Sugar Alcohols - pharmacology; Vertebrates: anatomy and physiology, studies on body, several organs or systems; Human; Energy balance; Energetic value; Nitrogen balance; Sucrose; Lactitol; Carbohydrate; Supplemented diet; Feeding
• ISSN: 0007-1145; 1475-2662
• DOI: 10.1079/BJN19860135

Extract: 1. Complete 24 h energy and nitrogen balances were measured for eight subjects both while consuming a basal diet supplemented with 49 g saccharose/d (diet S) and while consuming the same basal diet but supplemented with 50 g lactitol monohydrate/d (diet L). 2. The subjects ate the two diets for 8 d. Faeces and urine were collected for the final 4 d. Exchange of respiratory gases (oxygen, carbon dioxide, hydrogen and methane) was measured during the final 72 h while the subjects stayed in an open-circuit respiration chamber, 11 m3, and simulated office work. Before eating diet L, subjects ate 50 g lactitol daily for 10 d. 3. On diets L and S, faecal moisture content averaged 0.787 and 0.753 g/g respectively, the difference being significant (P less than 0.05). On diet L, energy and nitrogen digestibilities and energy metabolizability averaged 0.922, 0.836 and 0.881 respectively, and on diet S 0.935, 0.869 and 0.896 respectively; the differences were also significant (P less than 0.05). Urinary energy losses and N balances were not significantly different for the two diets. 4. In all subjects only traces of methane were produced but hydrogen production differed signifiantly (P less than 0.05) for diets L and S, being 2.3 and 0.4 litres (normal temperature and presure)/d respectively. 5. Intakes of metabolizable energy (ME) were corrected, within subjects, to energy equilibrium and equal metabolic body-weight. The corrected ME intakes did not show differences between diets. However, when on diet L the subjects were probably less active than when on diet S because differences within subjects of ankle actometer counts between diets showed a high correlation with the corresponding differences in corrected ME intakes (r 0.92). Further correction of ME intake toward equal actometer activity showed a significant (P less than 0.05) difference between diets: for maintaining energy equilibrium 5.6 (SE 0.8; P less than 0.05) % more ME from diet L was needed than from diet S. The reliability of this 5.6% difference depends on whether or not one ankle actometer gives an accurate picture of the subject's physical activity. 6. The energy contribution to the body is clearly smaller from lactitol than from saccharose, certainly due to the effect of lactitol on digestion, and probably also due to the effect on the utilization of ME.(author)