Industrial prospects for thermophiles and thermophilic enzymes

Reasons for enzyme instability are discussed. Thermophiles are a promising source of more stable intracellular enzymes. This aids their purification as well as providing desirable industrial properties. The organisms themselves have advantages for high temperature fermentations, e.g. for ethanol pro...

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Bibliographic Details
Published inBiochemical Society Symposia Vol. 48; pp. 133 - 146
Main Authors Hartley, B.S, Payton, M.A
Format Journal Article
LanguageEnglish
Published England 1983
Subjects
Anaerobiosis
Cloning, Molecular
Enzymes - metabolism
Ethanol - metabolism
Fermentation
food microbiology
food processing
Geobacillus stearothermophilus - genetics
Geobacillus stearothermophilus - metabolism
Hot Temperature
Hydrogen-Ion Concentration
L-Lactate Dehydrogenase - metabolism
Mutation
Protein Conformation
Species Specificity
Time Factors
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Summary:Reasons for enzyme instability are discussed. Thermophiles are a promising source of more stable intracellular enzymes. This aids their purification as well as providing desirable industrial properties. The organisms themselves have advantages for high temperature fermentations, e.g. for ethanol production. Systems for cloning genes into them are under development. An example is given of genetic and physiological manipulation of a fast-fermenting Bacillus stearothermophilus to increase ethanol yields at 70 degrees C similar to those obtained with yeasts.
ISSN:0067-8694
1744-1439