Minor Phenolic Constituents of the Anemarrhenae Rhizoma

A homoisoflavanone, 7,4'-dihydroxyhomoisoflavanone (1) and a flavanone, (2S)-7,4'-dihydroxy-5-methoxyflavanone (2), were isolated from the rhizomes of Anemarrhena asphodeloides, together with 4,4'-dihydroxychalcon (3), 2'-O-methylphlorethin (4), 1,3-bis-di-p-hydroxyphenyl-4-pente...

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Bibliographic Details
Published inNatural product sciences Vol. 15; no. 4
Main Authors Youn, U.J., Ewha Womans University, Seoul, Republic of Korea, Lee, Y.S., Ewha Womans University, Seoul, Republic of Korea, Jeong, H.N., Ewha Womans University, Seoul, Republic of Korea, Nam, J.W., Ewha Womans University, Seoul, Republic of Korea, Lee, Y.J., Ewha Womans University, Seoul, Republic of Korea, Son, Y.M., Ewha Womans University, Seoul, Republic of Korea, Hwang, E.S., Ewha Womans University, Seoul, Republic of Korea, Seo, E.K., Ewha Womans University, Seoul, Republic of Korea
Format Journal Article
LanguageEnglish
Published 01.12.2009
Subjects
Anemarrhena asphodeloides
Antiadipogenic activity
Homoisoflavanone
LILIACEAE
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Summary:A homoisoflavanone, 7,4'-dihydroxyhomoisoflavanone (1) and a flavanone, (2S)-7,4'-dihydroxy-5-methoxyflavanone (2), were isolated from the rhizomes of Anemarrhena asphodeloides, together with 4,4'-dihydroxychalcon (3), 2'-O-methylphlorethin (4), 1,3-bis-di-p-hydroxyphenyl-4-penten-1-one (5), and 2,4'-dihydroxy-4-methoxybenzophenone (6) on the basis of spectroscopic and physicochemical analyses including 1D- and 2D- NMR techniques as well as by comparison of their data with the published values. Compounds 1 - 4 were isolated for the first time from this plant source. Among isolates, compound 2 exhibited moderate inhibitory effect on the differentiation of pre-adipocyte 3T3-L1 cells.
Bibliography:2010001001
T10
ISSN:1226-3907