Injection of dextran sulphate enhances in mice the stimulatory influence of serum on growth of haemopoietic tissue colonies (GM-CFC) in vitro

A single i.p. injection of dextran sulphate elevates in mice the activity of blood serum for the stimulation of haemopoietic stem cell (GM-CFC) growth in vitro. Elevation of the stimulatory activity of serum persists up to 24 h after injection of dextran sulphate.

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Bibliographic Details
Published inFolia biologica Vol. 35; no. 4; pp. 261 - 265
Main Authors Vacek, A, Bartonickova, A, Rotkovska, D. (Ceskoslovenska Akademie Ved, Brno (Czechoslovakia). Ustav Biofyziky)
Format Journal Article
LanguageEnglish
Published Czech Republic 1989
Subjects
ANIMAL DE LABORATOIRE
ANIMALES DE LABORATORIO
Animals
BLOOD CELLS
BLOOD SERUM
CELL COUNTING
CELLULE SANGUINE
CELULAS SANGUINEAS
Colony-Stimulating Factors - physiology
CONTEO DE CELULAS
CRECIMIENTO
CROISSANCE
CULTIVO DE TEJIDOS
CULTURE DE TISSUS
Dextran Sulfate
Dextrans - pharmacology
DRUGS
ESTIMULO
EXPERIMENTACION IN VITRO
EXPERIMENTATION IN VITRO
FARMACOLOGIA
Granulocyte-Macrophage Colony-Stimulating Factor
GROWTH
Growth Substances - physiology
HAEMATOPOIESIS
HEMATOPOIESE
HEMATOPOIESIS
Hematopoietic Stem Cells - drug effects
Hematopoietic Stem Cells - physiology
IN VITRO EXPERIMENTATION
In Vitro Techniques
LABORATORY ANIMALS
MEDICAMENT
MEDICAMENTOS
MICE
NUMERATION CELLULAIRE
PHARMACOLOGIE
PHARMACOLOGY
RATON
SERUM SANGUIN
SOURIS
STIMULATION
SUERO SANGUINEO
SULFATE
SULFATOS
SULPHATES
TISSUE CULTURE
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Summary:A single i.p. injection of dextran sulphate elevates in mice the activity of blood serum for the stimulation of haemopoietic stem cell (GM-CFC) growth in vitro. Elevation of the stimulatory activity of serum persists up to 24 h after injection of dextran sulphate.
Bibliography:L70
9000076
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ISSN:0015-5500