NETWORK META-ANALYSIS OF RELATIVE EFFICACY AND SAFETY OF EDOXABAN VERSUS OTHER NOVEL ORAL ANTICOAGULANTS (NOACS) AMONG ATRIAL FIBRILLATION PATIENTS WITH CHADS2 SCORE ≥ 2

RELY ROCKET-AF ARISTOTLE ENGAGE-AF TIMI-48 Total patients in phase 3 trial 18,113 14,264 18,201 21,105 Years of follow-up (median) 2.0 1.9 1.8 2.8 Patients with CHADS2 score >= 2 68% 100% 66% 100% Patients with previous stroke or transient ischemic attack 20% 55% 19% 28% Patients with heart failu...

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Published inJournal of the American College of Cardiology Vol. 65; no. 10; p. A346
Main Authors Sherrill, Beth, Fernandez, Maria, Wang, Jianmin, Ye, Xin, Kwong, Winghan, Sherif, Bintu, Hogue, Susan
Format Journal Article
LanguageEnglish
Published New York Elsevier Limited 17.03.2015
Subjects
Anticoagulants
Cardiology
Cardiovascular
Drug therapy
Embolisms
Internal Medicine
Older people
Stroke
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Summary:RELY ROCKET-AF ARISTOTLE ENGAGE-AF TIMI-48 Total patients in phase 3 trial 18,113 14,264 18,201 21,105 Years of follow-up (median) 2.0 1.9 1.8 2.8 Patients with CHADS2 score >= 2 68% 100% 66% 100% Patients with previous stroke or transient ischemic attack 20% 55% 19% 28% Patients with heart failure 32% 62% 35% 57%
ISSN:0735-1097
1558-3597
DOI:10.1016/S0735-1097(15)60346-1