Renal transplant pathology : Bahrain experience

• Published in: Saudi journal of kidney diseases and transplantation Vol. 13; no. 1; pp. 71 - 76
• Main Authors: Datta, B. N., Ratnakar, Kamaraju Suguna, George, Sarah, Rajagopalan, S., Fayiq, al-Hilli, Farid, Iman, al-Tantawi, Muhammad Abd Allah, al-Arid, Samir, al-Arid, Ahmad
• Format: Journal Article
• Language: English
• Published: Riyadh, Saudi Arabia Saudi Center for Organ Transplantation 2002
• Subjects: Kidneys; Transplantation; الخزعة; الكلى; زرع الأعضاء; علم الأمراض
• ISSN: 1319-2442; 2320-3838

A ten-year retrospective study on renal transplant biopsies performed at the Salmaniya Medical Complex, Bahrain was performed. The histological changes were classified according to Banff 1997 working classification of renal allograft pathology. A semi quantitative scoring was also given as per the guidelines. Out of a total of 26 cases, 10 belonged to hyper acute and acute forms, while 11 could be categorized to chronic sclerosing allograft nephropathy. In the remaining five, the graft pathology was unrelated to the rejection process. Despite effective management, four cases underwent nephrectomy due to severe vascular rejection. An interesting feature was recorded in two cases in whom Trans mural arteritis followed chronic histological changes. Presence of tubular atrophy and interstitial matrix increase were considered useful parameters for assessing the severity in cases with chronic allograft nephropathy.