Sequence of a new tRNA Leu(U ∗AA) from brewer's yeast

The nucleotide sequence of a new tRNA Leu(anticodon U ∗AA) from Saccharomyces cerevisiae which could recognize exclusively the UUA codon has been determined. Its primary structure is: pGGAGGUUGm 2GCac 4CGAGDGmGDCDAAGGCm 2GGCAGACmUU ∗AAm 1GAΨCUGUUGGACGGUUGUCCGm 5CGCGAGTΨCGm 1A(orA)ACCUCGCAUCCUUCACCA....

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Bibliographic Details
Published inBiochimie Vol. 73; no. 11; pp. 1355 - 1360
Main Authors El Adlouni, C., Desgrès, J., Dirheimer, G., Keith, G.
Format Journal Article
LanguageEnglish
Published Elsevier Masson SAS 01.11.1991
Subjects
ARN
BREWERS YEASTS
LEVADURA DE CERVEZA
LEVURE DE BIERRE
NUCLEOTIDE SEQUENCE
primary structure
RNA
SACCHAROMYCES CEREVISIAE
SECUENCIA NUCLEICA
SEQUENCE NUCLEIQUE
tRNA Leu(U ∗AA)
yeast
primary structure
yeast
tRNA Leu(U ∗AA)
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Summary:The nucleotide sequence of a new tRNA Leu(anticodon U ∗AA) from Saccharomyces cerevisiae which could recognize exclusively the UUA codon has been determined. Its primary structure is: pGGAGGUUGm 2GCac 4CGAGDGmGDCDAAGGCm 2GGCAGACmUU ∗AAm 1GAΨCUGUUGGACGGUUGUCCGm 5CGCGAGTΨCGm 1A(orA)ACCUCGCAUCCUUCACCA. This tRNA has a large extraloop and contains 15 modified nucleotides. So far it is the third isoacceptor tRNA for leucine in yeast. It has 61% homology with tRNA Leu(anticodon m 5CAA) and 63% homology with tRNA Leu(anticodon UAG), the two other known yeast tRNAs Leu.
Bibliography:9201413
Q01
ISSN:0300-9084
1638-6183
DOI:10.1016/0300-9084(91)90165-W