Mechanisms of Cardiogenesis in Cardiovascular Progenitor Cells

• Published in: International Review of Cell and Molecular Biology Vol. 293; pp. 195 - 267
• Main Authors: Taubenschmid, Jasmin, Weitzer, Georg
• Format: Book Chapter Journal Article
• Language: English
• Published: Netherlands Elsevier Science & Technology 2012
• Subjects: Adult; Animals; Cardiogenesis; Cardiovascular progenitor cell; Cell differentiation; Cell plasticity; Embryonic Development - genetics; Embryonic Development - physiology; Heart - embryology; Humans; Models, Biological; Myocardium - cytology; Myocardium - metabolism; Organogenesis - genetics; Organogenesis - physiology; Self-renewal; Signal Transduction - genetics; Signal Transduction - physiology; Stem cell; Stem Cell Niche - genetics; Stem Cell Niche - physiology; Stem Cells - metabolism; Stem Cells - physiology; Transcriptional control; Self-renewal; Stem cell; Cardiovascular progenitor cell; Cell differentiation; Transcriptional control; Cardiogenesis; Cell plasticity

Self-renewing cells of the vertebrate heart have become a major subject of interest in the past decade. However, many researchers had a hard time to argue against the orthodox textbook view that defines the heart as a postmitotic organ. Once the scientific community agreed on the existence of self-r...