Spinal epidural abscess due to Aspergillus infection of the vertebrae: Report of 3 cases

• Published in: Netherlands journal of medicine Vol. 48; no. 1; pp. 18,19 - 18,23
• Main Authors: Dubbeld, P., van Oostenbrugge, R.J., Twijnstra, A., Schouten, H.C.
• Format: Journal Article Conference Proceeding
• Language: English
• Published: Alphen aan den Rijn Elsevier B.V 01.01.1996; Van zuiden
• Subjects: Abscess - complications; Abscess - diagnosis; Abscess - microbiology; Abscess - therapy; Acute Disease; Acute leukaemia; Adult; Aged; Aspergillosis - complications; Aspergillosis - diagnosis; Aspergillosis - therapy; Aspergillus infection; Biological and medical sciences; Cervical Vertebrae; Epidural spinal abscess; Female; Human mycoses; Humans; Immunocompromised Host; Infectious diseases; Leukemia, Myeloid - complications; Lumbar Vertebrae; Male; Medical sciences; Mycoses; Mycoses of the osteoarticular system; Spinal Diseases - complications; Spinal Diseases - diagnosis; Spinal Diseases - microbiology; Spinal Diseases - therapy; Aspergillus infection; Epidural spinal abscess; Acute leukaemia; Human; Nervous system diseases; Vertebral canal; Acute; Leukemia; Diseases of the osteoarticular system; Abscess; Malignant hemopathy; Spine disease; Fungi; Case study; Extradural; Aspergillus; Spondylitis; Complication; Fungi Imperfecti; Thallophyta
• ISSN: 0300-2977; 1872-9061
• DOI: 10.1016/0300-2977(95)00048-8

Aspergillus infection of the vertebral bodies and intervertebral disc spaces with consequent formation of a spinal epidural abscess was diagnosed in 3 patients with acute leukaemia. Medical therapy consisted of high-dose amphotericin-B with good local control of disease in one patient. The second patient underwent surgical drainage. The third patient had stabilisation of the disease. The clinical features, diagnosis and treatment are discussed.