Malignant epithelial neoplasia with hair follicle differentiation in dogs: Malignant pilomatrixoma

Epithelial neoplasia with hair follicle differentiation and malignant behaviour is described in two dogs. The neoplasia (solitary and multiple forms) were characterized by the proliferation of basaloid cells with central necrosis and the formation of shadow cells, keratin cysts, nests and whorls of...

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Bibliographic Details
Published inJournal of comparative pathology Vol. 86; no. 1; pp. 121 - 129
Main Authors Sells, D.M., Conroy, J.D.
Format Journal Article
LanguageEnglish
Published England Elsevier Ltd 1976
Subjects
animal diseases
animal health
Animals
Dog Diseases - pathology
Dogs
Hair - pathology
Male
noninfectious diseases
Skin - pathology
Skin Neoplasms - pathology
Skin Neoplasms - veterinary
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Summary:Epithelial neoplasia with hair follicle differentiation and malignant behaviour is described in two dogs. The neoplasia (solitary and multiple forms) were characterized by the proliferation of basaloid cells with central necrosis and the formation of shadow cells, keratin cysts, nests and whorls of squamoid cells containing keratohyalin or trichohyalin, and occasionally focal calcification. The tumours are compared with pilomatrixoma, trichoepithelioma, keratotic basal cell carcinoma and basosquamous carcinoma and are considered to be a malignant variant of the first of these.
Bibliography:ObjectType-Case Study-2
SourceType-Scholarly Journals-1
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ISSN:0021-9975
1532-3129
DOI:10.1016/0021-9975(76)90036-0