DETECTION OF PRE-PLAQUE AMYLOID AGGREGATION USING FTIR

• Published in: Alzheimer's & dementia Vol. 10; no. 4; p. P652
• Main Authors: Klementieva, Oxana, Engdahl, Anders, Faideau, Mathilde, Willén, Katarina Ingrid, Uvdal, Per, Gouras, Gunnar K
• Format: Journal Article
• Language: English
• Published: Elsevier Inc 01.07.2014
• Subjects: Basic Medicine; Clinical Medicine; Fysik; Klinisk medicin; Medical and Health Sciences; Medicin och hälsovetenskap; Medicinska och farmaceutiska grundvetenskaper; Natural Sciences; Naturvetenskap; Neurologi; Neurology; Neurosciences; Neurovetenskaper; Physical Sciences; Subatomic Physics; Subatomär fysik

Background: Alzheimer's disease (AD) is characterized by misfolding and aggregation of naturally occurring beta-amyloid peptides (Aβ). These aggregates are thought to be pathogenic to neurons, although the conformation of the pathogenic Aβ species remains unclear. Biochemical extraction methods...