The coronary profile: An approach to the preclinical diagnosis of coronary artery disease

• Published in: The American journal of cardiology Vol. 3; no. 5; pp. 579 - 586
• Main Authors: Talbott, G.Douglas, Keating, Bessie, Palmiere, Darwin, Hunsicker, Elmer
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.01.1959
• Subjects: Coronary Artery Disease; Coronary Disease - diagnosis; Heart; Humans; Old Medline; CORONARY DISEASE/diagnosis
• ISSN: 0002-9149; 1879-1913
• DOI: 10.1016/0002-9149(59)90337-6

The coronary profile approach to the preclinical diagnosis of coronary artery disease is presented, with results of a pilot project which suggest its reliability in identifying individuals imminently in danger of developing clinical coronary abnormalities. The coronary profile rating includes blood lipid chemistries (45 per cent), physical examination (20 per cent), resting and stress ECG (20 per cent), x-ray findings (10 per cent), and history (5 per cent). Clinical abnormalities suggestive of coronary artery disease were more common in those subjects with a poor profile rating (red zone) than in those with a higher rating (yellow and green zones). The potential values of this approach would appear to justify further investigation of its reliability and its possible modification into a simplified detection method with community-wide applicability.