The effect of hyperpotassemia on the idioventricular pacemaker in complete A-V heart block and comparison with its effect on the heart rate in normal sinus rhythm: An experimental study in dogs

Data are presented relative to the effects of varying degrees of hyperpotassemia on the atrial and ventricular rates in the presence of normal sinus rhythm and with complete A-V heart block. In the initial or moderately advanced stages of hyperpotassemia with serum levels up to 9.2 mEq./L. there is...

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Published inThe American journal of cardiology Vol. 7; no. 6; pp. 817 - 822
Main Authors Muller, Otto F., DeLeon, Antonio C., Bellet, Samuel
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 01.01.1961
Subjects
Animals
Atrioventricular Block
Dogs
Heart Block
Heart Rate
Humans
Hyperkalemia
Old Medline
Pacemaker, Artificial
Potassium - blood
POTASSIUM/blood
HEART BLOCK/experimental
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Summary:Data are presented relative to the effects of varying degrees of hyperpotassemia on the atrial and ventricular rates in the presence of normal sinus rhythm and with complete A-V heart block. In the initial or moderately advanced stages of hyperpotassemia with serum levels up to 9.2 mEq./L. there is only a slight change in the atrial and ventricular rates in the presence of normal sinus rhythm. However, in the presence of complete A-V heart block the ventricular rate shows a decrease of 51 per cent (± 3.61 per cent) from the control rate with serum potassium levels up to 7.75 mEq./L. (± 0.22 mEq./L.). The possible relationship between these elevated serum potassium levels and the occurrence of Stokes-Adams seizures in patients with complete A-V heart block is discussed.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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ISSN:0002-9149
1879-1913
DOI:10.1016/0002-9149(61)90400-3