Acetate selective fluorescent turn-on sensors derived using vitamin B6 cofactor pyridoxal-5-phosphate

• Published in: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy Vol. 157; pp. 110 - 115
• Main Authors: Sharma, Darshna, Kuba, Aman, Thomas, Rini, Ashok Kumar, S.K., Kuwar, Anil, Choi, Heung-Jin, Sahoo, Suban K.
• Format: Journal Article
• Language: English
• Published: England Elsevier B.V 15.03.2016
• Subjects: Acetate; Acetates - analysis; Aminophenols - chemistry; Aniline Compounds - chemistry; Anions - chemistry; Dimethyl Sulfoxide - chemistry; Fluorescent Dyes - chemistry; Fluorescent sensor; Limit of Detection; Models, Molecular; Pyridoxal Phosphate - chemistry; Schiff base; Schiff Bases - chemistry; Spectrometry, Fluorescence - methods; Vitamin B6 cofactor derivative; Schiff base; Fluorescent sensor; Acetate; Vitamin B6 cofactor derivative; Vitamin B cofactor derivative
• ISSN: 1386-1425; 1873-3557
• DOI: 10.1016/j.saa.2015.12.024

Two new Schiff base receptors have been synthesized by condensation of pyridoxal-5-phosphate with 2-aminophenol (L1) or aniline (L2). In DMSO, the receptors showed both chromogenic and ‘turn-on’ fluorescence responses selectively in the presence of AcO− and F−. However, in mixed DMSO–H2O medium, the receptors showed AcO− selective ‘turn-on’ fluorescence without any interference from other tested anions including F−. The detection limit for AcO− was found to be 7.37μM and 22.9μM using the receptors L1 and L2, respectively. [Display omitted] •Two new vitamin B6 cofactor derived anion receptors were introduced.•Receptors showed colorimetric selectivity for the sensing of F− and AcO− in DMSO.•Receptors showed ‘turn-on’ fluorescence towards AcO− in mixed DMSO–H2O medium.