Breathless in the Gut: Implications of Luminal O2 for Microbial Pathogenicity

Salmonella employs a variety of strategies to survive and colonize the colon. In this issue of Cell Host & Microbe, Rivera-Chávez et al. (2016) identify a new mechanism whereby antibiotic-mediated depletion of anaerobes (e.g., Clostridia) and associated decreases in butyrate result in increased...

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Bibliographic Details
Published inCell host & microbe Vol. 19; no. 4; pp. 427 - 428
Main Authors Kelly, Caleb J., Colgan, Sean P.
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 13.04.2016
Subjects
Anti-Bacterial Agents
Clostridium
Colon
Humans
Salmonella
Virulence
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Summary:Salmonella employs a variety of strategies to survive and colonize the colon. In this issue of Cell Host & Microbe, Rivera-Chávez et al. (2016) identify a new mechanism whereby antibiotic-mediated depletion of anaerobes (e.g., Clostridia) and associated decreases in butyrate result in increased tissue oxygen and increased aerobic expansion of Salmonella. Salmonella employs a variety of strategies to survive and colonize the colon. In this issue of Cell Host & Microbe, Rivera-Chávez et al. identify a new mechanism whereby antibiotic-mediated depletion of anaerobes (e.g., Clostridia) and associated decreases in butyrate result in increased tissue oxygen and increased aerobic expansion of Salmonella.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
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ObjectType-Commentary-1
ISSN:1931-3128
1934-6069
DOI:10.1016/j.chom.2016.03.014