Biomarker Sensitivity and Specificity Require Pre-Test Probability of Disease Diagnosis to Be Collated: Additional Points on the Interpretation of Pro–B-Type Natriuretic Peptide Triage of Dyspnea in the Copenhagen Heart Study

[...]the incremental value of proBNP testing is not clearly put in the context of clinical history; physical examination and simple bedside tests such as a 12-lead electrocardiogram and a chest roentgenogram. [...]proBNP levels can be elevated in lung conditions resulting in right heart strain and p...

Full description

Saved in:
Bibliographic Details
Published inJournal of the American College of Cardiology Vol. 51; no. 13; pp. 1322 - 1323
Main Authors MacFadyen, Robert J., Ng Kam Chuen, M. Jennyfer
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 01.04.2008
Elsevier Limited
Subjects
Biomarkers
Biomarkers - blood
Cardiology
Cardiovascular Diseases - blood
Cardiovascular Diseases - complications
Cardiovascular Diseases - diagnosis
Cardiovascular Diseases - physiopathology
Dyspnea - blood
Dyspnea - etiology
Dyspnea - physiopathology
Health Status
Heart
Humans
Natriuretic Peptide, Brain - blood
Peptide Fragments - blood
Probability
Risk Factors
Sensitivity and Specificity
Time Factors
Triage
Online AccessGet full text

Cover

More Information
Summary:[...]the incremental value of proBNP testing is not clearly put in the context of clinical history; physical examination and simple bedside tests such as a 12-lead electrocardiogram and a chest roentgenogram. [...]proBNP levels can be elevated in lung conditions resulting in right heart strain and pulmonary hypertension (10,11).
Bibliography:SourceType-Other Sources-1
content type line 63
ObjectType-Correspondence-1
ObjectType-Commentary-2
ISSN:0735-1097
1558-3597
DOI:10.1016/j.jacc.2007.11.063