The effects of Calotropis procera on small ruminants : I. Effects of feeding sheep with the plant

Fresh leaves of Calotropis procera fed to five sheep produced signs of toxicity and death of 4 of them between 33 and 83 days. Loss of appetite, diarrhoea, dyspnoea, alopecia and a steady deterioration of condition were the main clinical signs. The lesions consisted of hepatocellular necrosis and po...

Full description

Saved in:
Bibliographic Details
Published inJournal of comparative pathology Vol. 89; no. 2; pp. 241 - 250
Main Authors Mahmoud, O.M., Adam, S.E.I., Tartour, G.
Format Journal Article
LanguageEnglish
Published England Elsevier Ltd 1979
Subjects
Animals
Liver - pathology
Lung - pathology
Male
Myocardium - pathology
Plant Poisoning - blood
Plant Poisoning - pathology
Plant Poisoning - veterinary
Plants, Toxic
Sheep
Sheep Diseases - blood
Sheep Diseases - etiology
Sheep Diseases - pathology
Spleen - pathology
toxicity
Online AccessGet full text

Cover

More Information
Summary:Fresh leaves of Calotropis procera fed to five sheep produced signs of toxicity and death of 4 of them between 33 and 83 days. Loss of appetite, diarrhoea, dyspnoea, alopecia and a steady deterioration of condition were the main clinical signs. The lesions consisted of hepatocellular necrosis and portal fibrosis, catarrhal enteritis, splenic haemosiderosis, pulmonary congestion and oedema, haemorrhage in the heart and degeneration and/or necrosis of the cells of the renal convoluted tubules. These changes were accompanied by an increase in the concentration of ammonia, sodium, potassium and creatinine and a decrease in the concentration of total proteins and calcium in the serum. Haematological changes indicated the development of a normocytic normochromic anacmia.
ISSN:0021-9975
1532-3129
DOI:10.1016/0021-9975(79)90063-X