Polynucleotides: VI. The influence of various factors upon the structural transition of polyriboadenylic acid at acid pH's

Polyriboadenylic acid undergoes a pronounced structural transition in the vicinity of pH 6. This may be followed by spectral, hydrogen ion titration, or light-scattering methods. An increase in ionic strength serves to extend the region of transition to more acid pH's and also to accelerate the...

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Bibliographic Details
Published inBiochimica et biophysica acta Vol. 32; no. 1; pp. 166 - 176
Main Authors Steiner, R.F., Beers, R.F.
Format Journal Article
LanguageEnglish
Published Netherlands Elsevier B.V 01.03.1959
Subjects
Nucleosides
Nucleotides
Old Medline
Polynucleotides
NUCLEOSIDES AND NUCLEOTIDES
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Summary:Polyriboadenylic acid undergoes a pronounced structural transition in the vicinity of pH 6. This may be followed by spectral, hydrogen ion titration, or light-scattering methods. An increase in ionic strength serves to extend the region of transition to more acid pH's and also to accelerate the rate of transition at a given pH. Aggregation of the acid stable form is favored by increasing ionic strength or polymer concentration.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0006-3002
1878-2434
DOI:10.1016/0006-3002(59)90565-7