Plasma β-amyloid1–42 reference values in cognitively normal subjects

• Published in: Journal of the neurological sciences Vol. 391; pp. 120 - 126
• Main Authors: Zecca, Chiara, Tortelli, Rosanna, Panza, Francesco, Arcuti, Simona, Piccininni, Marco, Capozzo, Rosa, Barulli, Maria Rosaria, Barone, Roberta, Cardinali, Roberta, Abbrescia, Daniela, Seripa, Davide, Brescia, Vincenzo, Logroscino, Giancarlo
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 15.08.2018
• Subjects: Alzheimer's disease; Aβ peptide; Biomarker; Plasma; Reference values; β-amyloid; APP; Plasma; Biomarker; Aβ1–40; ALT; DSM-IV-TR; DP; Reference values; CDR; Aβ; SD; ANOVA; CSF; Hb; IC; Aβ1–42; SP; RIs; Alzheimer's disease; IFCC; BMI; β-amyloid; CLSI; AST; AD; Aβ peptide; ESR; HOMA Index; TSH; NINCDS-ADRDA; EDTA; MCI; CV; UPDRS-III; GGT; SPs; PET; ELISA

In clinical practice, the use of plasma β-Amyloid1–42 (Aβ1–42) as biomarker for Alzheimer's disease is largely limited by the absence of reference values. The aim of this study was to evaluate Aβ1–42 plasma concentrations in cognitively normal subjects and to propose reference values. Plasma sa...