Sex differences in dopamine systems involved in motivation and reward

In this chapter, we briefly discuss how to study sex differences as well as the four types of sex differences before discussing sex differences in dopamine regions involved in the reward system. There we discuss the development of sex differences in dopamine receptors and how ovarian hormones can mo...

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Bibliographic Details
Published inHandbook of Behavioral Neuroscience Vol. 32; pp. 383 - 393
Main Authors Turner, Christopher A., Bass, Noah, Gonzalez, Ivette L., Becker, Jill B.
Format Book Chapter
LanguageEnglish
Published Elsevier Science & Technology 2025
Subjects
Addiction
Behavioral neuroscience
Female reproductive endocrinology
Gender
Neuroscience
Neuroscience
Gender
Addiction
Female reproductive endocrinology
Behavioral neuroscience
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ISBN9780443298677
044329867X
ISSN1569-7339
DOI10.1016/B978-0-443-29867-7.00038-4

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Summary:In this chapter, we briefly discuss how to study sex differences as well as the four types of sex differences before discussing sex differences in dopamine regions involved in the reward system. There we discuss the development of sex differences in dopamine receptors and how ovarian hormones can modulate dopamine release and dopamine receptor function. We then discuss sex differences in motivated behavior in males and females, looking at rodents and humans. Gonadal hormones differentially affect dopamine receptor activity and stimulate dopamine release in specific brain regions, and this occurs differently in males and females. We discuss sex differences and hormonal influences on dopamine functions involved in motivation for food, sexual behavior, and drugs of abuse in rodents and in humans.
ISBN:9780443298677
044329867X
ISSN:1569-7339
DOI:10.1016/B978-0-443-29867-7.00038-4