녹용의 무기질 조성, 항산화능 및 PC-12 신경 세포 보호능에 대한 급여 사료의 영향

• Published in: KSBB Journal Vol. 27; no. 4; pp. 243 - 250
• Main Authors: 조치흥, 이봉한, 김해영, 김영채, 김대옥
• Format: Journal Article
• Language: Korean
• Published: 한국생물공학회 2012
• Subjects: 생물공학; Oxidative stress; Lactate dehydrogenase release; Total phenolics; Anti-neurodegenerative effect; Ash; Lactatedehydrogenase release
• ISSN: 1225-7117; 2288-8268
• DOI: 10.7841/ksbbj.2012.27.4.243

The ash content, mineral composition, total phenolics, antioxidant capacity, and neuroprotective effect of the antlers of deer fed with herb-incorporated feedstuff (HFS) or normal feedstuff (NFS) were comparatively evaluated. The contents of ash and mineral of the antler of deer fed with HFS were significantly lower than its counterpart. The ash and mineral contents of deer antlers decreased generally from the upper section toward the tip section. The ratios of Ca/ash, Ca/P, and Ca/Fe of antler of deer fed with HFS were lower than those of antler of deer fed with NFS. Antlers of deer fed with HFS had higher total phenolics, nitrite scavenging capacity, and antioxidant capacity than those of deer fed with NFS. Antlers of deer fed with HFS or NFS showed in vitro neuronal protection of PC-12 cells against oxidative stress in a dosedependent manner, where antler of deer fed with HFS generally had higher cellular viability than NFS. These results above suggest that the incorporation of the medicinal herbal complex into feedstuff may improve the biological effects of deer antlers.