The role of biofilm formation in the pathogenesis and antimicrobial susceptibility of Cutibacteriumacnes

Cutibacterium acnes (previously known as Propionibacterium acnes) is frequently found on lipid-rich parts of the human skin. While C. acnes is most known for its role in the development and progression of the skin disease acne, it is also involved in many other types of infections, often involving i...

Full description

Saved in:
Bibliographic Details
Published inBiofilm Vol. 4
Main Authors Coenye, Tom, Spittaels, Karl-Jan, Achermann, Yvonne
Format Journal Article
LanguageEnglish
Published Elsevier B.V 01.12.2022
Elsevier
Subjects
Antibiotics
Biofilm
Cutibacterium acnes
Antibiotics
Biofilm
Cutibacterium acnes
Online AccessGet full text

Cover

More Information
Summary:Cutibacterium acnes (previously known as Propionibacterium acnes) is frequently found on lipid-rich parts of the human skin. While C. acnes is most known for its role in the development and progression of the skin disease acne, it is also involved in many other types of infections, often involving implanted medical devices. C. acnes readily forms biofilms in vitro and there is growing evidence that biofilm formation by this Gram-positive, facultative anaerobic micro-organism plays an important role in vivo and is also involved in treatment failure. In this brief review we present an overview on what is known about C. acnes biofilms (including their role in pathogenesis and reduced susceptibility to antibiotics), discuss model systems that can be used to study these biofilms in vitro and in vivo and give an overview of interspecies interactions occurring in polymicrobial communities containing C. acnes.
ISSN:2590-2075
2590-2075
DOI:10.1016/j.bioflm.2021.100063