Research Status and Progress on Immunotherapy for Advanced Esophageal Squamous Cell Carcinoma in Hebei Province

Esophageal squamous cell carcinoma (ESCC) is one of the most prevalent gastrointestinal cancers in Hebei province. Most patients are diagnosed at an advanced stage due to untypical early symptoms, making surgical treatment often unfeasible. As a result, most of them are treated with comprehensive me...

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Bibliographic Details
Published inZhongliu fangzhi yanjiu Vol. 52; no. 2; pp. 103 - 109
Main Authors Duan, Xiaoyang, Shi, Jian
Format Journal Article
LanguageChinese
English
Published Tianjin China Anti-Cancer Association 01.02.2025
Magazine House of Cancer Research on Prevention and Treatment
Subjects
Cancer
Combined treatment
Effectiveness
Esophageal carcinoma
esophageal squamous cell carcinoma
Esophagus
Immunotherapy
Medical treatment
Patients
Prognosis
research progress
Squamous cell carcinoma
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Summary:Esophageal squamous cell carcinoma (ESCC) is one of the most prevalent gastrointestinal cancers in Hebei province. Most patients are diagnosed at an advanced stage due to untypical early symptoms, making surgical treatment often unfeasible. As a result, most of them are treated with comprehensive medical treatment, which tends to have limited effectiveness and poor prognosis. However, the recent introduction of immunotherapy has considerably advanced treatment options for patients with advanced ESCC, notably improving their prognosis. Uncertainties regarding immune resistance, the selection of predictive indicators of efficacy, the identification of dominant population, and the choice of combined treatment strategies are still evident. Therefore, based on the high incidence and poor prognosis of ESCC in Hebei Province, this article will briefly review the research progress in the treatment of advanced ESCC, aiming to provide guidance for treatment strategies for advanced esophageal cancer.
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ISSN:1000-8578
DOI:10.3971/j.issn.1000-8578.2025.24.0856