Developing a Color-Based Molecular Sensing Device: DETECHIP

DETECHIP® is a detection system made of various sensors that has been shown to detect and discriminate between small molecules of interest, including various illicit drugs for and over-the-counter medications, explosives, pesticides and food spoilage metabolites. DETECHIP® employs an array of sensor...

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Bibliographic Details
Published inSensors & transducers Vol. 183; no. 12; pp. 30 - 33
Main Authors Okuom, Macduff O, Holmes, Andrea E
Format Journal Article
LanguageEnglish
Published Toronto IFSA Publishing, S.L 01.12.2014
Subjects
Chromatography
Codes
Color
Colorimetric array
DETECHIP
Drug detection
Drug testing
NMR
Nuclear magnetic resonance
Prescription drugs
RGB Code
Sensor
Sensors
Studies
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Summary:DETECHIP® is a detection system made of various sensors that has been shown to detect and discriminate between small molecules of interest, including various illicit drugs for and over-the-counter medications, explosives, pesticides and food spoilage metabolites. DETECHIP® employs an array of sensors from which an analyte is tested and based on changes in color; a code specific to the analyte is developed. DETECHIP® offers possibilities for a simple, sensitive, selective, and affordable alternative to costly immunoassays. Results from NMR, UV-VIS and fluorimetry studies suggest that the color and fluorescence changes are a result of intermolecular interaction between the analytes and sensors ranging from non-covalent covalent bonding of supramolecular structure to proton exchange between the analyte and sensor molecules. Current efforts are focused on miniaturization of DETECHIP® to the micro and nanoscale.
ISSN:2306-8515
1726-5479