Recapitulation of SARS-CoV-2 infection and cholangiocyte damage with human liver ductal organoids

• Published in: Protein & cell Vol. 11; no. 10; pp. 771 - 775
• Main Authors: Zhao, Bing, Ni, Chao, Gao, Ran, Wang, Yuyan, Yang, Li, Wei, Jinsong, Lv, Ting, Liang, Jianqing, Zhang, Qisheng, Xu, Wei, Xie, Youhua, Wang, Xiaoyue, Yuan, Zhenghong, Liang, Junbo, Zhang, Rong, Lin, Xinhua
• Format: Journal Article
• Language: English
• Published: Beijing Higher Education Press 01.10.2020; Oxford University Press
• Subjects: Angiotensin-Converting Enzyme 2; Betacoronavirus - isolation & purification; Betacoronavirus - pathogenicity; Bile Acids and Salts - metabolism; Bile Ducts, Intrahepatic - pathology; Bile Ducts, Intrahepatic - virology; Biochemistry; Biomedical and Life Sciences; Cell Biology; Cell Culture Techniques; Coronavirus Infections - complications; Coronavirus Infections - pathology; COVID-19; Cytokine Release Syndrome - etiology; Cytokine Release Syndrome - physiopathology; Cytopathogenic Effect, Viral; Developmental Biology; Epithelial Cells - enzymology; Epithelial Cells - pathology; Epithelial Cells - virology; Human Genetics; Humans; Hyperbilirubinemia - etiology; Letter; Life Sciences; Liver - pathology; Organoids - pathology; Organoids - virology; Pandemics; Peptidyl-Dipeptidase A - analysis; Pneumonia, Viral - complications; Pneumonia, Viral - pathology; Protein Science; Receptors, Virus - analysis; SARS-CoV-2; Serine Endopeptidases - analysis; Stem Cells; Viral Load
• ISSN: 1674-800X; 1674-8018; 1674-8018
• DOI: 10.1007/s13238-020-00718-6