Quinazolinone and quinazoline derivatives: recent structures with potent antimicrobial and cytotoxic activities

The heterocyclic compounds have a great importance in medicinal chemistry. One of the most important heterocycles in medicinal chemistry are quinazolines possessing wide spectrum of biological properties like antibacterial, antifungal, anticonvulsant, anti-inflammatory, anti-HIV, anticancer and anal...

Full description

Saved in:
Bibliographic Details
Published inResearch in pharmaceutical sciences Vol. 11; no. 1; pp. 1 - 14
Main Authors Jafari, Elham, Khajouei, Marzieh, Hassanzadeh, Farshid, Hakimelahi, Gholam, Khodarahmi, Ghadam
Format Journal Article
LanguageEnglish
Published Iran Wolters Kluwer - Medknow Publications 01.01.2016
Medknow Publications and Media Pvt. Ltd
Medknow Publications & Media Pvt Ltd
Wolters Kluwer Medknow Publications
Subjects
Analysis
Azoles
Heterocyclic compounds
Quinazolinones; Quinazoline; Antimicrobial; Cytotoxic
Review
Antimicrobial
Quinazolinones
Quinazoline
Cytotoxic
Online AccessGet full text

Cover

More Information
Summary:The heterocyclic compounds have a great importance in medicinal chemistry. One of the most important heterocycles in medicinal chemistry are quinazolines possessing wide spectrum of biological properties like antibacterial, antifungal, anticonvulsant, anti-inflammatory, anti-HIV, anticancer and analgesic activities. This skeleton is an important pharmacophore considered as a privileged structure. This review highlights the recent advances in the synthesis of quinazolines and quinazolinone derivatives with potent antimicrobial and cytotoxic activities.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
ISSN:1735-5362
1735-9414