Consequences of Maternal Vitamin D Deficiency on Newborn Health

• Published in: Life (Basel, Switzerland) Vol. 14; no. 6; p. 714
• Main Authors: Dragomir, Ramona Elena, Toader, Daniela Oana, Gheoca Mutu, Daniela Elena, Dogaru, Iulian Alexandru, Răducu, Laura, Tomescu, Laurențiu Cezar, Moleriu, Lavinia Cristina, Bordianu, Anca, Petre, Ion, Stănculescu, Ruxandra
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 01.06.2024; MDPI
• Subjects: 25-Hydroxyvitamin D; Alfacalcidol; Anemia; Birth weight; Calcifediol; Calciferol; Complications and side effects; Correlation; Diseases; Fetuses; Gestational age; Health aspects; Impairment; Infants (Newborn); Insulin resistance; International studies; Maternal & child health; Medical laboratories; Metabolism; Neonates; newborn outcome; Obstetrical research; Physiology; Pregnancy; Pregnancy complications; Pregnancy, Complications of; Pregnant women; Proteins; Serum levels; Statistical analysis; Vitamin D; Vitamin D deficiency; vitamin D in pregnancy; Vitamin deficiency; Women; Womens health; Romania; vitamin D in pregnancy; vitamin D deficiency; newborn outcome
• ISSN: 2075-1729; 2075-1729
• DOI: 10.3390/life14060714

Maternal-fetal gestational pathology is one of the biggest challenges in the field of health at this moment. The current study is designed to determine the effects of vitamin D on pregnancy, starting with the idea that impairment of vitamin D status is thought to be correlated with impairment of the newborn's health. In this retrospective study, we tried to establish the link between vitamin D deficiency and maternal characteristics and also how it impacted the clinical status of the newborn. We analyzed a group of 260 patients: 130 pregnant women and 130 newborns, in whom vitamin D status was detected using the serum levels of 25-hydroxyvitamin D (25-(OH)D). The results showed that vitamin D deficiency has a high incidence among pregnant women, as was presented in many important international studies. Our study also showed a positive, direct correlation between the mother's and newborn's vitamin D status. Taking into consideration that vitamin D deficiency has been correlated with many complications, both in maternal and newborn health, a serum level determination of 25-(OH)D is necessary in the first trimester of pregnancy, and after that, adequate supplementation is necessary in order to prevent any negative effects.