Cardiac status in children with acute poststreptococcal glomerulonephritis
Acute poststreptococcal glomerulonephritis (PSGN) is the most common type of glomerulonephritis seen in children. It can affect multiple organs with heart being frequently involved. Yet, there are very few studies on cardiac status in children with PSGN and hence this study was conducted. All consec...
Saved in:
Published in | Saudi journal of kidney diseases and transplantation Vol. 28; no. 4; pp. 830 - 835 |
---|---|
Main Authors | , , |
Format | Journal Article |
Language | English |
Published |
Riyadh, Saudi Arabia
Saudi Center for Organ Transplantation
01.07.2017
Medknow Publications and Media Pvt. Ltd Medknow Publications & Media Pvt. Ltd Wolters Kluwer Medknow Publications |
Subjects | |
Online Access | Get full text |
Cover
Loading…
Summary: | Acute poststreptococcal glomerulonephritis (PSGN) is the most common type of
glomerulonephritis seen in children. It can affect multiple organs with heart being frequently
involved. Yet, there are very few studies on cardiac status in children with PSGN and hence this
study was conducted. All consecutive children from 1 month to 12 years of age, admitted over a
two-year period with a diagnosis of PSGN, were included in the study. An electrocardiogram
(ECG) and two-dimensional echocardiogram were performed in all patients on admission and
repeated at six and 12 weeks, if abnormal. A total of thirty patients (18 males and 12 females)
were enrolled in the study. The median age was six years. Prolonged QTc interval was found in
11 patients (37 %), of whom nine had hypertension. Seven of the 30 patients had a left ventricular
ejection fraction (LVEF) <60%. The same patients also had left atrium/aorta ratio >2 and E/A
ratio >2. LVEF returned to normal by six weeks in all except one patient, in whom it was normal
by 12 weeks. Two of seven patients with low LVEF had normal blood pressure. All the seven
patients recovered completely on follow-up. ECG and echocardiographic abnormalities may be
seen in the acute phase of PSGN but are usually transient, returning to normal in most patients by
three months. Although hypertension is the most common cause of cardiac failure, the role of
primary myocardial dysfunction should also be considered |
---|---|
Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 1319-2442 2320-3838 |