Tuberculosis disparity between US-born blacks and whites, Houston, Texas, USA

Tuberculosis (TB) rates in the United States are disproportionately high for certain ethnic minorities. Using univariate and multivariate analyses, we compared data for 1,318 US-born blacks with 565 US-born non-Hispanic whites who participated in the Houston TB Initiative (1995-2004). All available...

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Bibliographic Details
Published inEmerging infectious diseases Vol. 15; no. 6; pp. 899 - 904
Main Authors Serpa, Jose A, Teeter, Larry D, Musser, James M, Graviss, Edward A
Format Journal Article
LanguageEnglish
Published United States U.S. National Center for Infectious Diseases 01.06.2009
Centers for Disease Control and Prevention
Subjects
African Americans - statistics & numerical data
bacteria
Drug resistance
epidemiology
European Continental Ancestry Group - statistics & numerical data
Genetic aspects
Health Status Disparities
Human immunodeficiency virus
Humans
Incidence
minorities
Molecular Epidemiology
Multivariate Analysis
Mycobacterium tuberculosis
Mycobacterium tuberculosis - classification
Mycobacterium tuberculosis - genetics
Mycobacterium tuberculosis - isolation & purification
Population Surveillance - methods
Risk Factors
Texas
Texas - epidemiology
Texas - ethnology
Tuberculosis
Tuberculosis - epidemiology
Tuberculosis - ethnology
Tuberculosis - microbiology
Tuberculosis - prevention & control
tuberculosis and other mycobacteria
Tuberculosis, Multidrug-Resistant - epidemiology
Texas
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Summary:Tuberculosis (TB) rates in the United States are disproportionately high for certain ethnic minorities. Using univariate and multivariate analyses, we compared data for 1,318 US-born blacks with 565 US-born non-Hispanic whites who participated in the Houston TB Initiative (1995-2004). All available Mycobacterium tuberculosis isolates underwent susceptibility and genotype testing (insertion sequence 6110 restriction fragment length polymorphism, spoligotyping, and genetic grouping). TB in blacks was associated with younger age, inner city residence, HIV seropositivity, and drug resistance. TB cases clustered in 82% and 77% of blacks and whites, respectively (p = 0.46). Three clusters had >100 patients each, including 1 cluster with a predominance of blacks. Size of TB clusters was unexpectedly large, underscoring the ongoing transmission of TB in Houston, particularly among blacks.
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ISSN:1080-6040
1080-6059
DOI:10.3201/eid1506.081617